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Description
Improving blood sugar levels, with diet and exercise, in patients with type 2 diabetes who are already being treated with both of these medicines or who are not adequately controlled on metformin alone.
Avandamet is a combination of an insulin resistance reducer and a biguanide. This combination medicine works in 2 ways to improve blood glucose levels (sugar). Rosiglitazone helps the cells use glucose, and metformin slows the liver's production of glucose. Controlling high blood sugar helps prevent heart disease, strokes, kidney disease, blindness, circulation problems, and sexual function problems (impotence).
Do NOT use Avandamet if:
1) you are allergic to any ingredient in Avandamet
2) you have kidney problems
3) you have type 1 diabetes; lactic acidosis; metabolic acidosis, including diabetic ketoacidosis; or diabetic coma
4) you have congestive heart failure that requires treatment with medications
Contact your doctor or health care provider right away if any of these apply to you.
Recommendations
Take Avandamet preferably with meals.
Avandamet may take effect within 1 to 2 weeks after beginning therapy. However, full effects may not occur for 2 to 3 months.
Carefully follow the dietary guidelines and exercise plan given to you by your health care provider.
For best results, it is important to take Avandamet regularly. To help you remember, take your dose at the same time each day.
If a dose is missed, take it as soon as possible. If several hours have passed or if it is nearing time for the next dose, do not double the dose to catch up, unless advised by your doctor. If more than 1 dose is missed, restart medication and advise your doctor or pharmacist at your next appointment.
Precautions
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Diarrhea; metallic taste; trauma; weight gain.
Lactic acidosis, which can be fatal, may occur while taking Avandamet. Symptoms include general body discomfort, muscle pain, breathing problems, increasing drowsiness, upset stomach, cold skin, dizziness, tiredness, lightheadedness, and slowed heartbeat. If this does occur, seek medical attention at once.
Lactic acidosis is more likely to occur in patients who have heart failure, kidney or liver problems, excessive alcohol use, a lack of body fluids or dehydration, x-ray or scanning procedures that require an injectable iodinated contrast drug, surgery, serious infection, heart attack, or stroke. Also at higher risk are the elderly, especially those older than 80 years of age who have not had kidney and liver function tests.
Thiazolidinedione antidiabetics such as Avandamet may cause or worsen heart failure in some patients. Tell your doctor if you have a history of heart failure. Avandamet should not be used to treat patients with moderate to severe heart failure. You will be monitored for signs of heart failure when you start Avandamet and when your dose increases. Contact your doctor at once if you develop swelling of the hands, ankles, or feet; shortness of breath; or sudden unexplained weight gain. Your doctor may need to stop your medicine or change your dose.
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Canadian Health&Care Mall LTD is licensed online pharmacy, international license number 02724941 issued 10 January 2001
Canadian Health Care Shop is licenced by Minnesota Board of Pharmacy
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Main Office (headquarters)
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LA 71201-3659ICS
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